Blar i Bergen Open Research Archive på forfatter "Brekke, Ranveig Seim"

Viser treff 1-2 av 2

    • Characterization of insertion variants of the carboxyl-ester lipase (CEL) gene - A role in pancreatic disease? 

      Brekke, Ranveig Seim (Master thesis, 2018-06-26)
      Carboxyl ester lipase (CEL) is a digestive enzyme that is mainly expressed in the acinar cells of the pancreas. The CEL gene is highly polymorphic due to a variable number of tandem repeat (VNTR) region in the last exon. ...

    • The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice 

      Fjeld, Karianne; Svanbring, Anny Gravdal; Brekke, Ranveig Seim; Alam, Jahedul; Wilhelm, Steven J.; el Jellas, Khadija; Pettersen, Helene Nazmiye; Lin, Jianguo; Solheim, Marie Holm; Steine, Solrun; Johansson, Bente Berg; Njølstad, Pål Rasmus; Verbeke, Caroline Sophie; Xiao, Xunjun; Lowe, Mark E.; Molven, Anders (Journal article; Peer reviewed, 2022)
      Background & aims: The CEL gene encodes the digestive enzyme carboxyl ester lipase. CEL-HYB1, a hybrid allele of CEL and its adjacent pseudogene CELP, is a genetic variant suggested to increase the risk of chronic pancreatitis ...